MEETING TOPICS Repeat Instability, Fragile Sites, and DNA Replication and Repair Fragile X and Friedreich’s Ataxia Loss-Of-Function Polyglutamine/Polyalanine/Protein Gain-Of-Function RNA Pathogenesis: DM1, DM2, SCA8, SCA10, HDL2, FXTAS Epigenetic dysregulation, locus- and tissue-specific mechanisms Treatment Strategies

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